10 Best CoQ10 Ubiquinol Supplement
Coenzyme Q10 - a spark for power
Coenzyme Q10, or in another name called ubiquinone, is a fat-soluble substance, which resembles the fat-soluble vitamins E and K. It plays a central role in the body when it comes to energy production. Q10 is used to convert energy into body energy in every body cell.
It is a vitamin-like substance, which the body can produce in principle if it has enough folic acid, niacin and the vitamins B5, B6, B12 as well as the amino acids phenylalanine, tyrosine and methionine; But the ability to do so already drops at the age of twentieth. In the middle age, production has already declined by 30 - 40%, and by 80% by 60%. Functional disorders occur as a result of a deficiency of 25 per cent, a drop of 75 per cent upward is considered life-threatening. The reasons for the strong decrease are, in addition to reduced self-production, a lower intake and an increased demand by free radicals (oxidative stress). The body-specific preparation is reduced in particular by cholesterol-lowering drugs (statins).
There is an increased need for stress, strong muscle work, sports, high alcohol consumption, infections, heart muscle weakness, muscle wasting, thyroid hyperfunction, diabetes, Alzheimer's and Parkinson's. Drugs such as statins, Parkinson's drugs, cancer drugs, antidepressants, and beta-blockers additionally increase the need.
Coenzyme Q10 is the spark that activates the “mitochondrial motors” in the body cells and thus makes energy generation possible at all, so it plays a key role in the body. Each cell contains more than 500 “energy centers” (mitochondria), which are responsible for the communication in the cells and between the cells with their complex metabolism. This metabolism is brought to a lasting end by many stressful factors such as environmental pollution, heavy metals (e.g., mercury from amalgam globes), metabolic disorders, deficiency of vital substances, disturbance of the “immune system intestine.” Here, substances such as vitamins, minerals, amino acids and coenzyme Q10 are helpful to regain a healthy balance.
At the same time, Q10 acts as a cell protection factor by rendering harmful oxygen radicals, which are produced as a byproduct of energy production, which protects the cell structures from oxidative damage. Coenzyme Q10 can renew vitamin E as well as vitamin C.
Three major functions of this substance are given in the literature
Coenzyme Q10 is an important fat-soluble antioxidant. Metabolism: Q10 is present as a major energy supplier in all mitochondria (power plants of the cells). The highest concentrations are found in the organs with the largest energy requirement such as heart and liver, pancreas and kidneys. Q10 supports metabolic functions by stabilizing cell membranes.Immune System: Coenzyme Q10 improves the immune function in the body cells. Application areas for coenzyme Q10
Dr. Petra Wenzel describes the following fields of application for coenzyme Q10. “Eye disorders: antioxidant effect Cardiovascular system: improved cardiac function and strength, reduced heart attacks (angina pectoris) and cardiac arrhythmias (100-500 mg daily), Q10 can reduce blood pressure by approximately 10 percent in patients with hypertension (100 – 300 mg daily).Cholesterol lowering medication: Here the additional intake of Q10 is a must, as these drugs suppress the production of coenzyme Q10 … Cancer diseases: protection together with other antioxidants; 20% of cancer patients have a lowered Q10 level.
Muscular dystrophy: This is often accompanied by a malfunction of the mitochondria. When 2 mg/kg of body weight coenzyme Q10 (in combination with further, especially antioxidative nutrients) the muscle strength improved significantly. Nervous system: In the case of multiple sclerosis, Alzheimer’s disease and Parkinson’s disease, there are positive results for the use of approximately 500 mg coenzyme Q10 daily. Burnout: 50 – 200 mg daily; Migraine: 200-300 mg Sport: Intensive training significantly increases the need for coenzyme Q10. Sufficient Q10 increases the maximum oxygen intake prevents muscle damage and reduces muscle pain.
Metabolism: Coenzyme Q10 reduces the oxidative stress in diabetes mellitus, which is responsible for the late complications of blood vessels and nerves. It does not affect the blood glucose and insulin levels. In an energy-reduced diet, coenzyme Q10 can promote weight loss.Stress: Injuries, operations, and chronic diseases significantly increase the need for coenzyme Q10. Dentistry: It improves the condition of the oral mucosa, reduces inflammation and strengthens the hold of the teeth. Periodontal prophylaxis (90 – 300 mg daily) “As far as the overview of the possibilities of application of Dr. Wenzel. We will deal later in detail with the individual areas.
In the 1980s, numerous clinical studies were conducted with coenzyme Q10, which showed preventive and therapeutic effects in various diseases, especially in cardiovascular diseases, cancer, migraine and Parkinson’s disease. A study published in Archives of Neurology in October 2002 (source: Earl Mindell: The new Vitaminbibel, Heyne 2007) suggests that coenzyme Q10 can “slow down the progression of Parkinson’s disease. Certainly, further studies need to be carried out, but these initial results are very promising. So far, there are drugs that can alleviate the symptoms of Parkinson’s disease, but none of the currently known therapies can slow the progression of this disease. The researchers believe that coenzyme Q10 works by increasing the function of mitochondria, the “power” that produces the energy in the cells – especially since previous studies have shown that coenzyme Q10 levels in the mitochondria of Parkinson’s patients were altered. “
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What is the "Vitaminpapst" Mindell?
"... the cells need coenzyme Q10 for the respiratory process, and deficits are a normal companion of aging. Studies have even shown that diminished values of this coenzyme (which in combination with vitamin E have many antioxidant properties) can contribute directly to aging and that an increase in the values not only delays this process but also:
Reduces the risk of myocardial infarction (promotes tissue cell growth in the heart, supports the protection against inflammatory processes in the heart caused by viruses, prevents cardiac arrhythmias, reduces myocardial injury due to cardiac bypass surgery, and reduces the frequency of angina -pectoris seizures)
- Stimulates the immune system
- The treatment of gum disease
- Reduces the blood pressure
- The toxicity of drugs used to treat many age-related diseases
The micronutrient researcher Jeroen van Lunteren and the medical specialist author Hermann Ehmann write in their joint book “Vitamins help heal” (literature list) to CoQ10:
“CoQ10 (ubiquinone) is one of the most important micronutrients at all. In over 300 studies, the effects of Q10 have now been investigated. Recent research has shown that the antioxidant effect is even higher than previously thought. The main effect of Q10 is the reduction of oxidized LDL cholesterol. Among other things, it has been shown that Q10 increases life expectancy by preventing hereditary diseases and strengthening the immune system. Deficits are the rule from the age of 30.
Important: Q10 has no depot effect, i.e., the substance only acts as long as it is delivered. For persons with slight hypertension, the blood pressure lowering effect (100 – 400 mg daily) may also be interesting. In Japan, Q10 is one of the oldest and most widely used dietary supplements … Folkers / Langsjoen have demonstrated in a clinical study that the bioavailability (measured by the heart function) of coenzyme Q10 improves significantly when fed together with food fats. “
Step-by-step filling of the Q10 stores in the body
The Q10 level in the body changes slowly and step by step until normalization is achieved by means of a dietary supplement containing coenzyme Q10. The coenzyme is first used to replenish the Q10 memory and is only available for additional tasks. How quickly Q10 unfolds its effect in our body depends essentially on the physical condition and the existing Q10 mirror. Coenzyme Q10 can be effective after a few days if the deficit is very high. When the CoQ10 deficiency is low, the mirror slowly increases until it has normalized. This normalization process can take up to 3 months. Short-term, low-dose revenues are of little use. Coenzyme Q10 should be taken at least for a period of three months.
What happens with CoQ10 deficiency?
If the Q10 content in the blood is 25 percent below the saturation level, the tissue is damaged. It is possible to prove that the mitochondria change and their function is increasingly restricted. The cells can no longer produce enough energy and become more susceptible to oxidative stress caused by free radicals. This reduces performance and weakens the immune system of the body.
Causes of the Q10 deficiency are in addition to the already self-production already diminished with increasing age anyway:
Stress: Continuous stress loads always have a direct impact on free radicals on a physical level. This consumes Q10, which can no longer adequately fulfill its proper function of energy production in the cells because it is consumed to neutralize the free radicals.
Diseases: Here too, oxidative stress is created, which consumes Q10. Since only 2 to 5 milligrams of Q10 is taken daily with food on average, stress situations can not be compensated for. Incidentally, the widespread civilization disease of hypertension is severely burdening the Q10 household.
Medication: The use of certain drugs, especially cholesterol lowering, lowers the coenzyme Q10 level in the body
Nutrition: Today’s dietary craving due to the slim line leads to a lack of antioxidants due to insufficient food intake, which is always a burden on the Q10 household, so that there is not enough energy available. In addition, our food contains less and less Q10.
Selenium deficiency: For the liver to produce coenzyme Q10, it needs almost all vitamins and the trace element selenium. It is a component of the enzyme glutathione peroxidase, which neutralizes very effective free radicals. An under supply with Q10 can cause a selenium deficiency as a basic cause.
Coenzyme Q10 values in the body. The CoQ10 level in micrograms (μg) per milliliter of blood is:
Healthy: 0.85 μg
Allergic persons: 0.65 μg
Performance athletes: 0.60 μg
Angina pectoris: 0.55 μg
Chronic fatigue: 0.48 μg
Obesity (fat growth): 0.45 μg
Multiple Sclerosis: 0.42 μg
Chronic stress: 0.40 μg
Cardiac insufficiency: 0.28 μg
Tinnitus: 0.26 μg
How and in which quantity is CoQ10 Ubiquinol Supplement used?
The dosage of Coenzyme Q10: For health care 1 – 2 capsules of 30 mg daily, for prescriptions and diseases up to 150 mg and more. An intake of 60 – 100 mg coenzyme Q10 per day doubled the Q10 level in the blood. The additional intake of coenzyme Q10 does not affect the body’s synthesis; The organism maintains its normal production, even if food supplements are taken.
Lunteren / Ehmann recommend in the already mentioned book: “The dosage recommended in the literature is: Less than 40 years 30 to 60 mg From about 40 years, about 100 mg.
Cardiac patients may under medical supervision consider the intake of 200 to 300 mg, in cancer patients are often given 300 to 400 mg. In the case of breast cancer, 390 mg of Q10 have been successfully administered (clinic in Copenhagen). Consumers with increased stress (smokers, athletes, stress) can increase the dose without care. Side effects are not known even with higher and permanent dosage. “
It is best to take the coenzyme with a meal, which also contains some fat. As a fat-soluble substance, it is thus best absorbed. Overdosage: Even at very high doses of 600 mg daily no significant side effects have been observed. A supplemental supply of coenzyme Q10 can naturally improve the energy yield in cells, organs, and muscles. The sustainability of this measure is significantly increased by years of regular intake.
By the way: It takes a little time for the coq10 mirror to normalize again in the body. The establishment of Q10 reserves in mitochondria and cell walls requires at least four to five days, even at a high dose of 300 mg daily. For a daily intake of 10 to 30 mg per day, it takes three or more months for many people until a saturation value is reached at all. In this case, it is advisable to take 100mg daily for several weeks before transferring to a lower duration dosing. The dose should be increased if the patient is experiencing major stress or an increasing incidence of disease.
10 Best CoQ10 Ubiquinol Supplement Brands
The following is our list of best CoQ10 products based on personal testing, science backing, and online reviews without bias.
Qunol Mega's specially-formulated (solubilized) ubiquinol dissolves 100% in water and fat, providing superior absorption. With Qunol Mega Ubiquinol, optimum blood levels of CoQ10 are reached in just weeks—not months as with regular CoQ10.
Doctor’s Best High Absorption CoQ10 with BioPerine is an easy-to-absorb form of a key nutrient that powers and protects the body’s high-energy organs & systems – especially the heart & blood vessels.
Jarrow Formulas QH-absorb is a proprietary enhanced stability formula, which has been clinically shown in humans to increase Co-Q10 levels up to 777% (6.14x) over baseline at 300 mg per day intake.
I love it.
Kirkland Signature Ubiquinol provides 200 mg of CoQ10 as Ubiquinol and 30 IU of vitamin E. Coenzyme Q10 (CoQ10) helps support heart function and helps neutralize free radicals in the body. It is found in nearly every cell of the body and is a key component in cellular energy production.
Ubiquinol has powerful antioxidant actions in target cells although ubiquinone (oxidized coenzyme q10) and ubiquinol (reduced coenzyme q10) are kept at a constant ratio within the body, the majority of the total coenzyme q10 pool is made up of ubiquinol.
+ Antioxidant that helps maintain heart health
+ Liquid softgel
+ No artificial flavors natural 100%
+ If you are a veggie, you better take this one.
Garden of Life introduces RAW CoQ10--a powerful formula that delivers 200mg of RAW CoQ10 per serving. Featuring a unique lipid delivery system--a RAW cold-pressed chia seed oil omega 3-6-9 matrix--and 22 RAW and organically grown fruits and vegetables--fat soluble RAW CoQ10 supports cardiovascular system health, cellular energy production and antioxidant protection.
9. Pure CoQ10
100% Pure Coenzyme Q10 Antioxidant is free of extraneous fillers, binders and artificial ingredients. This supplements are always formulated in GMP compliant and FDA registered facilities, subjected to stringent third party purity testing, and made in the USA.
Ubiquinol CoQ10 absorbs up to 8 times better than ubiquinone CoQ10. PrimaVie® shilajit enhances mitochondrial CoQ10 absorption
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